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Effect of tripeptide Pro-Gly-Pro on rat brain transcriptome in focal ischemia

Loren Pickart identified over 4,000 genes influenced by GHK-Cu, with 31% upregulated and 35% downregulated

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In this model, the reduced anti-tumor immunity of sleep-deprived animals was also indexed by the reduced number of antigen-presenting cells (dendritic cells) in the lymph nodes, as well as by the decreased effector CD4 T-cell numbers and corresponding cytokine profile (decreased IFN-), resulting in lowered Th1 response of Th cells, i.e., the most effective immune response against tumors

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