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PMC7726887

Under stress, mitochondria release proinflammatory mediators, such as ATP, cardiolipin, ROS, and mtDNA, which, when released into the cytoplasm or extracellular space, can promote inflammation and trigger senescence or senescence-associated chronic diseases [208]

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After 6 months on the low carbohydrates diet, serum levels of neurofilament light chain, a biomarker of neuroaxonal damage, were significantly reduced compared with regular diet in patients with relapsing-remitting MS (171)