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Candidates for research or therapeutic application include those with primary or secondary insomnia, difficulty initiating or maintaining sleep, or disrupted circadian rhythms

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All samples were labeled with N -(2-aminoethyl) rhodamine 6G-amide bis(trifluoroacetate) (R6G) by using the EDC/NHS coupling reaction with a weight ratio of polypeptide to R6G at 20:1 (Fig

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