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In particularly, ACSL4 plays a crucial role in regulating ferroptosis, and its overexpression boosts the synthesis of -pufa6 PUFA and encourages ferroptosis (51)

For ferroptosis inducers combined with immune checkpoint inhibitors, sequential administration may maximize efficacy: initial ferroptosis induction promotes immunogenic cell death and antigen release, followed by checkpoint blockade to enhance T-cell activation and memory formation (236)

*You can also read about Ashwagandha Detoxification One of it's key functions is detoxifying harmful substances, especially in the liver, where it helps remove drug residues and environmental toxins

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Thyroid hormone receptor- agonists prevent hepatic steatosis in fat-fed rats but impair insulin sensitivity via discrete pathways