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All experimental procedures were carried out at the Gazi University Animal Laboratory following ethical guidelines approved by the Gazi University Experimental Animal Ethics Committee (G..ET-24.075)

[4] [5] In human cells, biotin is covalently attached to five specific carboxylase enzymes that catalyze critical steps in the metabolism of fatty acids, glucose, and amino acids
Vitamin B12 is thought to help with healing of blisters and the pain associated with Shingles

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Without enough B12, there can be some damages in nerve function, which can lead to symptoms such as tingling and numbness
