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ExTraMATCH II study, a meta-analysis that evaluated data from 3990 patients and 13 randomized trials (including HF-ACTION trial) showed a reduced rate of hospitalization and improved quality of life (QOL) in HFrEF patients

Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR

Furthermore, using a murine cholangitis model, the researchers clarified the underlying mechanisms: butyrate activates peroxisome proliferator-activated receptor delta (PPARD) to promote fatty acid -oxidation (FAO)-mediated metabolic reprogramming