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Ooi C, 2025, The Prevalence of pks + E

23 studies were excluded as they were post-mortem studies

In HTN, chronic activation of Ang II and NOXs overwhelms this system, leading to Nrf2 dysfunction or exhaustion, which exacerbates ROS accumulation, endothelial dysfunction, and vascular remodeling

Ermer, T., Eckardt, K

Relationship between astrocyte and neuron energy metabolism (including lactate shuttle and glutathione shuttle) While models of astrocyte-neuron metabolic coupling, such as the lactate and glutathione (GSH) shuttles, are well-supported, their universality and pathophysiological relevance remain subjects of debate