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2014;34:e00160
on the other hand, glutamine-derived isotopologues such as citrate m + 4, fumarate m + 4 and m + 2 (second round of oxidation), malate m + 4 and m + 2 (second round of oxidation), as well as aspartate m + 4 (coming from oxaloacetate directly or indirectly produced from the TCA as a result of further citrate oxidation in the cytoplasm) and m + 5 (originating from transamination reaction using labeled amine from glutamate and labeled carbons from oxaloacetate) are indicative of oxidative glutaminolysis (Fig

A strong jet of water striking the powdered lyophilizate directly can mechanically damage (denature) the sensitive peptide structure

The plate was sealed, vortexed for 5 min, and centrifuged at 4000 rpm for 3 min

Resection of Pulmonary & Extra-Pulmonary Sarcomatous Metastases is Associated with Long-term Survival
