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In one phase Ib/II study, 19 patients with R/R AML received combination therapy with azacitidine and avelumab, another PD-L1 inhibitor, with a higher CRR of 10.5%, and two patients achieved CR with thrombocytopenia (Saxena et al., 2021)

5 (2018): e3015

The teratogenic effect of Cu was checked using D

4 Transaminase Upregulation and Targeting Amino Acid Synthesis for Cancer Therapy Another means of inhibiting glutaminolysis is to target alanine transaminase through L-cycloserine or aspartate transaminase through the inhibitor amino oxyacetate, which could almost completely halt the growth of breast cancer in xenograft mice [117, 118]

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