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Because cartilage lacks blood vessels, it receives nutrients through diffusion, which limits its ability to repair itself

High blood levels thus achieved have therapeutic value

Subsequently, in a study of RAW264.7 and BMM cells, it was found that the water-soluble active ingredient of SM, protocatechuic aldehyde, reduced osteoclast formation and bone resorption, and inhibited osteoclast differentiation by inhibiting NF-B and MAPK signaling pathways (Qu et al., 2021)

Recently, Meng et al