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Oxidized GSH (GSSG) is reduced back to GSH by GSR in an NADPH-dependent manner, thereby sustaining cellular antioxidant defense and linking redox buffering to central metabolic pathways that generate NADPH, such as the PPP and IDH-dependent reactions

Wang F, An S-J, Yin Y, et al

[DOI] [PubMed] [Google Scholar] 10.Atalay Guzel N, Erikoglu Orer G, Sezen Bircan F, Coskun Cevher S

Similar content being viewed by others Introduction Ferroptosis is a type of cell death that depends on iron, involving free radicals and lipid metabolism, leading to iron-dependent lipid peroxidation and ultimately cell death

Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, et al
