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these changes do not make it a growth-hormone secretagogue, instead they sharply reduce its binding to IGF-binding proteins (IGFBPs), which is what extends its circulating half-life and potency relative to native IGF-1

Introduction: Why Your Facewash Choice Matters More Than You Think Ever wondered why your skincare routine feels incomplete even after washing your face twice a day

Biochem Soc Trans 34, 711, 10.1042/BST20060007 (2006)
