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While the reaction of the therapeutic antibody seems relatively straightforward on the myeloma side (as MM cells are FcR-negative), more complex interactions occur with effector cells (FcR + ), where the antibody can engage both the Fab-binding site and one of the FcRs on the same cell ( Figure 3 ) (110)

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Patients requiring enhanced antiviral defense and faster recovery from common infections

If symptoms arise, you do not know which compound caused the issue

Knowing the type of EDS/HSD gives you and your medical support team some idea of where problems might come from and why they are happening