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However, despite their health benefits, the low absorption rate of polyphenols (approximately 510% via the small intestine) and their rapid metabolism and excretion significantly limit their ability to reach target tissues (114)
(PubMed) Yang B, Fan S, Zhi X, et al

Unlocking mammalian regeneration through hypoxia inducible factor one alpha signaling
Also referenced as P21 , it is frequently used in laboratory models examining synaptic plasticity models and cellular response mechanisms

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