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[DOI] [PubMed] [Google Scholar] Perez MA, Magtanong L, Dixon SJ, Watts JL
Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management under the brand name Mounjaro and for chronic weight management as Zepbound
An ipTM score above 0.8 indicates high confidence in the prediction, while scores between 0.6 and 0.8 are considered a grey area, and scores below 0.6 are likely failed predictions
72 Upregulation of AMPD3 has been reported to impair energy metabolism in OLETF hearts
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