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Description
One prevailing theory is that tirzepatide is an imbalanced and biased GLP-1 RA with very low efficacy for recruitment of -arrestin, whilst is acting as an unbiased GIP agonist with full efficacy for -arrestin recruitment [51, 52]

PMID 11352721

10.1038/sj.npp.1301559 Neuropsychopharmacology 63 ClearyD
The net effect: you're burning more fat and storing less

Cognitive Market Research, 2025
