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This finding not only supports KPV's candidacy as a research compound for IBD investigation but also unveils a paradigm for drug delivery, exploiting alterations in protein expression to enhance drug localization and activity

administration in the BALB/c hippocampi may be associated with the mechanisms of peptides nootropic and anxiolytic activities manifested specifically in this mouse strain

Furthermore, the alteration of this complex resulted in reduced BDNF transport and subsequent release [17]

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While selectivity over classical ERs is reported at relevant concentrations, nuclear-receptor cross-reactivity and downstream network effects remain theoretical risks in longer or higher-exposure studies