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Water distribution depends primarily on the concentration of electrolytes in the body compartments and sodium (Na+) plays a major role in maintaining physiologic equilibrium

Both compounds produce clinically significant weight loss, but they achieve it through pathways that don't overlap

Drug Interactions Because these peptides influence vascular, inflammatory, and neurological pathways, interactions with anticoagulants, NSAIDs, immunosuppressants, psychiatric medications, and other pharmaceutical agents are possible but largely unexplored

6) Design Space: A range of acceptable values for the CMAs and CPPs within which the desired CQAs are consistently achieved are defined