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B12 is water-soluble, and excess is excreted, so the priority is steady intake rather than occasional very high doses

When substances are given orally they must be processed through the stomach and the intestines which decreases the absorption rate to 10%-20%

* Correspondence: Jian-ren Ye, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

This may cause other ailments such as tiredness, breathing difficulties, weakness, and vomiting

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