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Kang R, Zeh HJ, Lotze MT, Tang D (2011) The Beclin 1 network regulates autophagy and apoptosis

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As random changes tend to fluctuate, a steady progressive increase is unlikely to be due to chance

[DOI] [PMC free article] [PubMed] [Google Scholar] 408.Jensen H.S., Callo K., Jespersen T., Jensen B.S., Olesen S.P

The result is a discrete pulse of GH release subject to normal somatostatin-mediated negative feedback, theoretically preserving pulsatility, unlike exogenous recombinant GH which produces sustained non-physiologic serum levels