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Description
Parkin, 465-amino acid residue E3 ubiquitin ligase protein
ROS has been shown to be elevated in cancer cells due to their increased metabolism and hypoxic environment (Hayes et al
These results imply that the TBK1-p62 axis may play a role in HBV infection
The glutathione adduct can be secreted from cells via a membrane transporter
However, unlike necrosis, pyroptosis was initially described as a type of programmed cell death that, rather than being quiet, like apoptosis, triggers a robust inflammatory response, including the recruitment of immune cells to the site of death (Thornberry et al., 1992)
