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A total of 115 pathways were identified via the KEGG enrichment pathway analysis, including the HIF 1 signaling pathway, thyroid hormone signaling pathway, hepatitis B, Kaposi sarcoma associated herpesvirus infection, proteoglycans in cancer, renal cell carcinoma, PD L1 expression and PD 1 checkpoint pathway in cancer, Yersinia infection, influenza A, tuberculosis, neutrophil extracellular trap formation, viral carcinogenesis, lipid and atherosclerosis, vascular endothelial growth factor (VEGF) signaling pathway, chemical carcinogenesis-reactive oxygen species, shigellosis, prolactin signaling pathway, central carbon metabolism in cancer, adherens junction, EGFR tyrosine kinase inhibitor resistance, ErbB signaling pathway, prostate cancer, endocrine resistance, choline metabolism in cancer, Chagas disease, Toll like receptor signaling pathway, Ctype lectin receptor signaling pathway, growth hormone synthesis, secretion and action, platelet activation, and relaxin signaling pathway (Fig

doi: 10.1158/1078-0432.CCR-22-0784 7 KroemerGPouyssegurJ

& del Pozo (2013)

It does this by helping produce energy within the sperms mitochondria

For these patients, L-carnitine supplementation is a life-saving treatment