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Succinate and fumarate are intermediates in TCA cycle, while R-2-HG and S-2-HG as enantiomers are both byproducts with low concentration in normal cellular metabolism, while the accumulation of them greatly increased in abnormal circumstances [100]

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Interaction of Candida albicans with Adherent Human Peripheral Blood Mononuclear Cells Increases C

Peerj 11 (12), 739741

Indeed, pathways of regulated cell death including apoptosis and necrosis have emerged as central events in the pathogenesis of various kidney diseases that may be amenable to therapeutic intervention