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At the distribution stage, caffeines effect on increasing the tightness of the bloodbrain barrier is important as it may impede the passage of important drugs into the central nervous system, including memantine and donepezil used in the pharmacotherapy of Alzheimers disease

For instance, when applied in the morning, it works synergistically with sunscreen to combat UV-induced damage, reducing the risk of photoageing

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Short-term testicular warming under anesthesia causes similar increases in testicular blood flow in Bos taurus vs
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