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It is recommended that liver enzymes be monitored on a monthly basis in all animals receiving ketoconazole or itraconazole
Earlier studies have found that mitochondria are not only the main sources of ROS, but also the main tools for clearance (34)
After adding 800 L of cold MeOH/H2O to the frozen tissue, a pellet pestle (Sigma-Aldrich, UK) was used to homogenize the tissue for 1 min
Participants were mostly younger ( 30) (Voroneanu, J Diabetes Res, 2016) [17]
Nature Chemical Biology 17, 549557
