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Of the 27 dogs: 22% had an elevated MMA value, indicative of vitamin B12 depletion at the tissue level
Thus, the macrophage-based strategy for drug delivery harnesses the prolonged circulation time, abundant surface receptors, and active targeting ability of macrophages under specific phenotype
22 Homeostasis In principle, these concepts 14 - 25 consider homeostasis, (cytoprotection/adaptive cytoprotection, organoprotection) as the organs protection from injury as well as organs recovery after injury, as the most important result
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Neuroscientist 22 , 447463 (2016)
