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The activation of astrocytes may be involved in the addiction process
These findings were further corroborated by a preclinical work where Parkinson rats (induced by intraperitoneal injection of 1-Methyl-4-phenyl-1,2,3,6- tetrahydropyridine, 20 mg/kg) recorded the highest depletion in dopamine concentration and highest lipid peroxidation activity following 60 days of oral intake of alcohol compared to cigarette inhalation or frequent mating (Ambhore et al., 2012
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Dehydroepiandrosterone (DHEA) or testosterone were used as substrates for 3-HSD or 17-HSD, respectively
