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NAC takes the sulfur from glutathione and connects it to toxic molecules, which then become water-soluble to be excreted from the body

(2) Oxidative Stress (Top Right): Inflammation-driven excessive reactive oxygen species (ROS) generation and the collapse of antioxidant defense systems (e.g., SOD, CAT, GPx, and the Nrf2/HO-1 pathway) lead to lipid peroxidation and the accumulation of oxidative damage markers (MDA, 8-OHdG)

167 , 168 Nevertheless, years of research have resulted in significant breakthroughs in understanding PZA's mode of action

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