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2180-LB: Bimagrumab augments metabolic rate to improve incretin-induced weight loss in obese mice

Compared with the OC group, the liver TG level, total liver TC level and liver weight of the mice in the Lira intervention group were significantly reduced

U.S.A 106 (2) (2009) 422427

By preventing highfat dietmediated changes to the levels of important proteins involved in lipid homeostasis, including fatty acid synthase (FAS), AMPactivated protein kinase (AMPK), and sirtuin1 (SIRT1), walnut supplementation reduced the accumulation of fat

Lysis was performed in 3 cycles of vortexing for 30 s, incubation in liquid nitrogen for 1 min followed by subsequent thawing at room temperature and sonication for 10 min in an ice-cold water bath