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Proc Natl Acad Sci United States America (2019) 116(25):1251623
10.1007/s10787-020-00714-6 140 ZhangY
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Interestingly, the expression of IGF-I and IGF-IR is profoundly reduced in the growth plates of the Cart CaSR / mice (44), suggesting that Ca 2+ /CaSR promotes chondrocyte differentiation, at least in part, by enhancing IGF-I signaling (Figure 1)
