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Fluorescence microscopy studies have documented rapid cellular accumulation, with detectable intracellular concentrations within 30 minutes of external application at physiological concentrations

Because its not regulated as a pharmaceutical, whats in the vial doesnt always match whats on the label

[DOI] [PubMed] [Google Scholar] 99.Mady F.M., Abou-Taleb A.E., Khaled K.A., Yamasaki K., Iohara D., Ishiguro T., Hirayama F., Uekama K., Otagiri M

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A special fibre jacket (artificial annulus) has been developed to mimic the AF in the so-called NP explant system, creating a physiological model to test the efficacy of regenerative therapies for IVD degeneration [15, 17]