JPP No 5/2013 article 09
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Okuda M, Li K, Beard MR, Showalter LA, Scholle F, Lemon SM & Weinman SA (2002) Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein
The structure of dehydroascorbic acid, the first oxidation product of ascorbic acid, has been analyzed by X-ray crystallography to be a dimer (Figure 1c)
doi: 10.1016/s1388-1981(00)00044-5
Freezing denatures the peptide structure and renders the medication ineffective, even if it thaws afterward
however, their number was too small to conduct a separate analysis in subgroups
