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Standard oral fluid drug tests use the same panel structure as urine and blood tests

10.1016/j.phymed.2023.155169 37 DiergeE.DebockE.GuilbaudC.CorbetC.MignoletE.MignardL.et al (2021)

L.ShimozawaM.et al (2022)

Notably, although both CCKRs adopt the canonical seven-transmembrane architecture, they differ from other reported class-A GPCRs with a shortened TM4 helix, which is attributed to the unwinding of the helix at the extracellular half caused by the presence of P 4.59 and the additional P 4.61 (the superscripts refer to the BallesterosWeinstein number) 44