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Recent studies have revealed that the NLRP3 inflammasome is activated in the brain to induce neuroinflammation, leading to further neuronal damage and functional impairment, and contributes to the pathological process of various neurological diseases, such as multiple sclerosis, Parkinsons disease, Alzheimers disease, and stroke

I think we can use that to guide us in a much more effective way than just clinging to, you know, handfuls of SNPs and drawing conclusions about our health from that

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However, for the sake of completeness, we also note that there is also a single reference that HoloTC is not superior to total B 12 [84]