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Description
The concept of enhanced lactate production was first described a century ago by the Warburg effect, which revealed that tumor cells rely on anaerobic glycolysis even in the presence of oxygen, providing them with numerous advantages
TXNIP, in particular, achieves bidirectional autophagy regulation by engaging with distinct target proteins, such as the metabolic regulators mTOR and AMPK, the stress sensor REDD1, the master transcription factor TFEB, and by influencing the PI3K/Akt/mTOR signaling pathway

Overly rounded purity values (e.g., always exactly 99%)

doi: 10.1007/s12026-012-8312-8

These responses occur within half an hour and activate multiple cellular signaling mechanisms, supporting the statement that the cellular response to metal ions and the following signaling pathways are integrated in a signal transduction process [124]
