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The situation is further compounded by the presence of posttranslational modifying factors, such as kinase activities and S -glutathionylation
However, these models are predominantly developed based on the prediction of molecular physiochemical properties, which is not designated to BBBP specific task and may not fully capture the specific molecular features associated with BBB penetration
10.1016/j.jep.2010.09.008 116 MilkovicL.Cipak GasparovicA.CindricM.MouthuyP
Carcinoma-associated fibroblasts affect sensitivity to oxaliplatin and 5FU in colorectal cancer cells
The earlier phase of the syndrome is Wernicke encephalopathy ( encephalopathy literally means disease of the brain)
