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The American Academy of Family Physicians and NIH identify the following clinical manifestations: Fatigue and generalized weakness Megaloblastic anemia (abnormally large, immature red blood cells) Tingling or numbness in the hands and feet (peripheral neuropathy) Difficulty walking and balance problems Cognitive disturbances including memory difficulty and confusion Mood changes, including depression and irritability Glossitis (swollen, inflamed tongue) Early symptoms such as fatigue and mild tingling are often attributed to stress, aging, or other conditions

The formulation and route of administration of iron is based on tolerability and previous response to treatment

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Glutathione plays a crucial role in protecting cells from oxidative stress, which is implicated in the pathogenesis of many diseases, including neurodegenerative disorders, cardiovascular diseases, and liver diseases