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doi: 10.1182/blood-2012-11-427765

9 , e2003699 (2022)

Between 1.5% and 15% of the public has a vitamin B12 deficiency, and certain groups are at a higher risk: Older Adults : As we age, our bodies may produce less stomach acid, which is necessary to absorb B12 from food

Crosstalk of reactive oxygen species and nf-b signaling

Chronic exposure to mental stress, anxiety, or depression can lead to abnormal activation of the hypothalamicpituitaryadrenal axis, resulting in sustained cortisol elevation [116]
