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About SS-31 (Elamipretide) is a synthetic mitochondria-targeting tetrapeptide that binds cardiolipin in the inner mitochondrial membrane, enhancing electron transport chain efficiency and reducing oxidative stress

Griffiths JI, Chen J, Cosgrove PA, et al

A clinical study following people with CF on elexacaftor/tezacaftor/ivacaftor (ETI) for 6 months found a significant reduction in antibiotic use by the end of the studysuggesting a lower prevalence of bacterial-induced exacerbations (Nichols et al., 2022)

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Protein extracts were then subjected to SDSPAGE and transferred to Immobilin-FL polyvinylidene fluoride transfer membrane