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As the common epigenetic regulation mechanisms, DNA methylation, histone modification, and non-coding RNA regulation have been well studied

In: Levy RH, Thummel KE, Trager WF et al

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*Correspondence: Shuyu Zhang, [email protected] These authors have contributed equally to this work This article was submitted to Molecular and Cellular Oncology, a section of the journal Frontiers in Oncology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Runt-related transcription factor 2 Runt-related transcription factor 2 has diverse functions and plays an important role in maintaining the balance of bone metabolism in osteoporosis by regulating the differentiation, development and growth factor expression of osteoblasts [42, 43]