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Theoretically, NAC should be supplied at a 1:1 molar ratio with NAPQI, one of the major hepatotoxic metabolites
GSTT1 and GSTM1 polymorphisms predict treatment outcome for acute myeloid leukemia: A systematic review and meta-analysis
Protein Oxidation ROS can alter protein structure through a process called protein carbonylation, impairing enzyme function and cellular signalling
Amsterdam: Elsevier (2016)
Another possible mechanism could be the ability of GR to maintain reduced glutathione concentrations in tissues even at low activity levels ( Reference Rogers and Augusteyn 31 )
