glutathione metal complex stability constants Glutathione: a naturally occurring tripeptide for functional nanomaterials The Formation Constants of Mercury(II)−Glutathione

Among them, the upregulation was most remarkable in lesional PN skin, reaching levels 50 times higher than those in healthy skin

In breast cancer, RNF5 loss is associated with increased ASCT2 expression, finally leading to poor patient outcomes, and poor response to paclitaxel (Ma et al., 2021), colon cancer (Ma et al., 2018), pancreatic cancer (Wang et al., 2022), and TNBC (Van Geldermalsen et al., 2016)

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Unfortunately, a phase II clinical trial of UBX0101 (NCT03513016) was completed in patients with osteoarthritis and the promising results observed (Table 1), in vitro and in vivo, have not been up to the expectations in treated patients, leading only to a decrease of pain, without a significant improvement of the disease 30