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The rise in 8-OHG levels holds particular significance as it signifies RNA oxidative damage, which plays pivotal roles in protein synthesis and other essential cellular functions ( 5 Conclusion Our study highlights the profound metabolic perturbations induced by -lactam antibiotics in E.coli , elucidating distinct yet overlapping effects across different antibiotic classes

Dosage protocols used in preclinical research vary depending on the study design and research objectives

and reduced litter size, embryonic survival, and placental function in females