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Together, these data suggest that in heterogeneous non-NE/NE SCLC tumors, fractional killing via ferroptosis may select for NE cells over time while, vice versa, TRX pathway inhibition might enrich tumors for non-NE SCLC cells

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Mol Biol Cell 15 : 176188 Carratu R et al

Furthermore, to refine the experimentally determined structural model and explore interaction dynamics, we conducted extensive MD simulations

2018XLC1007)
