dihexa peptide neurotrophic cognitive AngIV-Analog Rescues Impairment and Recovers Memory in the APP/PS1 Mouse via the PI3K/AKT Signaling Pathway Dihexa - PRAMAH / THE

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The introduction of the R17 Cagri- E14 Cagri intra-peptide ionic lock energetically favours the formation of a predominant bypass conformation at the CTR, which, together with the P37 substitution and the effects induced by the N-terminal acylation, likely underlies its improved potency over rAmy at this receptor

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doi:10.1016/b978-0-444-54299-1.00006-6

The Pei 2024 meta-analysis has a larger total patient pool (1,458 vs 472), giving it more overall statistical power