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Description
NAD+: Supports mitochondrial energy production in hormone optimization protocols

This leads to cAMP generation and activates cAMP-dependent protein kinase (PKA), which in turn promotes the relaxation of airway smooth muscle cells through phosphorylation of cross-bridge cycling regulatory proteins

That does not mean AOD 9604 is worthless
Therapeutic concentrations of salicylates and prednisolone show concentration-dependent protein binding

Those who accept that this is a supportive tool not a magic bullet and are willing to pay for clinician supervision, quality sourcing, lab monitoring