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Cells characterized by rapid division (epithelial cells, bone marrow, myeloid cells) appear to have the greatest requirement for cyanocobalamin

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The logic is synergistic: provide the raw material (NR/NMN) while simultaneously blocking the leak (5-Amino-1MQ) to maximize cellular NAD+ levels

The results showed statistically significant but clinically modest weight loss (2kg average advantage over placebo at the 1mg oral dose over 23 weeks)