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Description
Metabolic Studies in Obese Zucker Murine Models An early preclinical study evaluated the metabolic implications of AOD-9604 in obese Zucker rats, a validated rodent model of obesity characterized by leptin receptor deficiency and hyperphagia
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Kimberlin RH, Collis SC, Walker CA
Regulatory bodies like the FDA and EMA necessitate thorough physicochemical characterisation, stability information, and proof of therapeutic equivalency, which can be challenging for these heterogeneous systems [124]
