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J Endocrinol 188 : 589601 Teilum K et al

miR-125a-5p promotes M1 macrophage polarization by downregulating IL-1 receptor antagonist protein, thereby activating the Toll-like receptor (TLR)4/myeloid differentiation primary response 88/TNF receptor-associated factor 6/NF-B signaling pathway and enhancing its pro-inflammatory effects (67)

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The relative frequencies are based on 2500 referred cases
