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They reduce the effects of aging

From Trans-Methylation To Cytosine Methylation: Evolution Of The Methylation Hypothesis Of Schizophrenia

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By inhibiting this enzyme, A1AT decreases the production of superoxides, contributing to a reduction in the overall ROS burden in tissues and helping to limit oxidative damage ( Furthermore, A1AT binds to metal ions such as copper (Cu) and iron (Fe), which catalyze ROS production via the Haber-Weiss and Fenton reactions